InVivo
Population health

InVivo turns personal tracking into measurable population-healthspan value.

The population-health opportunity is a consented loop: source-grounded events, modality-focused UX, source-fidelity SleepInsight recovery evidence, preventable transition models, governed low-cost interventions, CarePlan packets, Triager handoffs, measured outcomes, economic endpoints, and honest safety boundaries.

Model families
5

metabolic, cardio, recovery, inflammation, function

Pilot protocols
11

every declared intervention has a measurable protocol

CarePlan loop
closed

packets, handoff, compliance, outcome review

SleepInsight FL
7 tasks

sleep/wake, acoustic, recovery, uplift, metabolic response

Native parity
2

iOS Twin readiness plus Android domain parity

Report rule
>=3

minimum cohort cell before aggregate display

Source-grounded health events

Every signal can carry time, source, method, confidence, privacy class, consent scope, and source receipt metadata so population models are built from auditable evidence instead of unstructured wellness notes.

Preventable transition models

InVivo models transitions that can be prevented or delayed: worsening metabolic recovery, cardiovascular marker momentum, SleepInsight recovery debt, persistent inflammation context, and functional decline.

Governed intervention loops

The native model layer implements measurable protocols with eligibility, required inputs, preferred inputs, burden, cost, measurement windows, prohibited-use withholding, and aggregate-safe reporting.

CarePlan follow-up evidence

Standards-backed CarePlans now become consent-scoped Clinician Packets: included, withheld, stale and missing evidence; source receipts; Triager handoff context; observed effects; and reviewable signals for how a plan may need clinician review.

SleepInsight recovery evidence

Sleep becomes a source-grounded nightly recovery event: source fidelity, sanity validation, user corrections, breathing-load boundaries, HRV/resting-heart-rate context, and derived-feature cohort eligibility.

Cohort learning with consent

Individuals get personal feedback while consented cohorts can reveal which low-cost actions work, where data is missing, and which groups need better measurement before stronger claims are made.

Cost and utilization endpoints

Population value is measured through avoided duplicated labs, completed follow-up, lower user burden, clinician minutes saved, low-cost intervention adherence, and healthier daily function.

Privacy-preserving boundaries

Population reporting is aggregate-safe, small-cell suppressed, consent-scoped, and explicit about what remains personal, what can be shared, and what is never diagnosis or medication advice.

Model families

Model preventable transitions, not abstract wellness.

The current implementation focuses on five healthspan model families and ties every declared intervention to measurable assignment, adherence, outcome, and reporting contracts.

Metabolic deterioration

Transition: Stable metabolic pattern -> poor glucose recovery or higher-risk lab band

Action
post-meal walking, earlier dinner, DPP-style prevention packet
Endpoint
glucose recovery, lab anchors, adherence, cost per improved risk state

Cardiovascular momentum

Transition: Stable marker pattern -> unmanaged BP, lipid, glucose, or recovery momentum

Action
home BP plan, lipid packet, follow-up preparation
Endpoint
duplicate tests avoided, clinician minutes saved, marker drift prevented

Recovery capacity

Transition: Stable recovery -> SleepInsight recovery debt, lower adherence, or fewer functional days

Action
sleep regularity, strain budget, meal cutoff, wind-down plan
Endpoint
source-fidelity sleep timing, HRV/resting HR, correction rate, healthy functional days

Inflammation context

Transition: Weak context -> persistent abnormal marker pattern needing clinician discussion

Action
repeat-lab packet, symptom timing, recovery-load review
Endpoint
unnecessary worry/testing avoided while preserving escalation

Function and frailty prevention

Transition: Stable function -> mobility decline, lower strength reserve, or falls context

Action
strength habit, protein adequacy, walking consistency, mobility check
Endpoint
functional days preserved and avoidable decline reduced
Pilot suite

Eleven protocols make the portfolio assignable and reportable.

Post-meal walking keeps the deepest glucose-specific outcome scoring; the full suite adds structured eligibility, SleepInsight recovery endpoints, CarePlan activity assignment, consent-scoped Clinician Packets, stale or withheld evidence, Triager handoffs, prohibited-use withholding, follow-up assessment, and small-cell-suppressed cohort reports across all five model families.

01

Eligibility

Check source coverage, protocol-specific required inputs, missing preferred inputs, readiness, and prohibited medical-use triggers before assigning a pilot.

02

CarePlan assignment

Select a declared protocol or standardized CarePlan activity with an action label, measurement window, required source context, and safety boundary.

03

Compliance evidence

Capture completion, burden, source count, SleepInsight correction labels, Clinician Packet readiness, stale or withheld evidence, and safety handoffs rather than assuming a recommendation was followed.

04

Outcome window

Measure response using predefined endpoints such as glucose recovery, BP coverage, SleepInsight sleep regularity, packet follow-up, functional days, duplicate testing avoided, or CarePlan goal movement.

05

Aggregate learning

Report only cohort-safe counts, adherence, missingness, response distribution, burden, economic endpoints, and plan-modification hypotheses with small-cell suppression.

Metabolic14 days

Post-meal walk

meal adherence and 30/60/120-minute glucose response

Metabolic7 days

Earlier dinner

overnight recovery, morning glucose or ketone context

Metabolic90 days

DPP-style prevention

packet review, activity minutes, weight/waist or lab follow-up

Cardio14 days

Home BP tracking

reading consistency, source provenance, follow-up readiness

Cardio30 days

Lipid clinician packet

clinician review, duplicated tests avoided, source-document utility

Recovery7 days

Sleep regularity

source-fidelity sleep timing, HRV/resting HR, correction rate, recovery debt, functional-day reports

Recovery7 days

Strain budget

accepted suggestions, correction rate, next-day recovery

Inflammation45 days

Repeat-lab context

repeat-lab completion, escalation preserved, duplicated explanation avoided

Inflammation14 days

Recovery-load review

symptom resolution, recovery movement, lab-anchor timing

Function28 days

Strength habit

session adherence, walking consistency, soreness, functional-day report

Function30 days

Mobility check

mobility-check completion, walking trend, escalation completion

Anecdote falsification

Patient-led experiments become governed prevention evidence.

InVivo Experiments turns wellness folklore into pre-specified, randomized, safety-screened n-of-1 trials. ProvidEHR consents, source-grounds, and federates the results — so a claim collapses or refines on evidence, without centralizing raw personal data.

Pre-specified

Hypothesis, population, exclusions, endpoints, and minimum worthwhile effect are fixed before the first day of data.

Federated, not centralized

Phones compute personal effects and contribute only secure-aggregated summaries — federated analytics first, learning second.

Stricter verdicts

Supported, falsified, not-supported-in-cohort, subgroup signal, inconclusive, or stop — never the word 'proved'.

Clinically linkable

Promoted to clinical-grade only with a pre-registered protocol, CONSORT-style reporting, external validation, and clinician review.

The ProvidEHR position

ProvidEHR turns patient-led experiments into governed prevention evidence: consented, source-grounded, federated, and linked to clinical outcomes.

How a claim becomes governed evidence
01

Consented

Each claim is a distinct, withdrawable opt-in under research consent — and because experiment data can touch care, clinical linkage is a separate consent beyond general uploads.

02

Source-grounded

Every reading carries time, source, method, confidence, and consent scope; baseline labs or validated scores anchor the endpoint, so the evidence is auditable, not self-reported anecdote.

03

Federated

Phones compute each person's effect locally and contribute only secure-aggregated sufficient statistics — never raw readings — with small-cell suppression before anything is reported.

04

Governed verdict

An inverse-variance cohort estimate is judged against a pre-specified minimum worthwhile effect, with adverse-event stop rules and the stricter supported / not-supported / subgroup / inconclusive vocabulary.

05

Linked to outcomes

Promotion to clinical-grade requires pre-registration, CONSORT-style reporting, external validation, and clinician review — then the verdict can inform CarePlans and is tracked against real care outcomes.

Who it serves

Health systems and research partners get consented, source-grounded prevention evidence instead of influencer claims — with explicit missingness and subgroup calibration.

What stays private

Raw observations never leave the phone. Only masked summaries are aggregated, and small cells are suppressed, so no individual experiment is exposed.

Where it stops

Experiments that change prescribed therapy are clinician-directed, never self-started. The boundary — wellness and clinician discussion — is part of the evidence.

ProvidEHR can say which patient-led experiments helped, which did not, and when burden or risk outweighed benefit — preserving privacy throughout. That is governed evidence, not wellness content.

See the falsification engine
Governance

The product boundary is part of the value.

InVivo can support population-health learning without turning the app into a diagnosis, prescribing, or surveillance system.

Health systems

CarePlan follow-through

Identify which standardized plans produce measurable follow-through, which evidence is ready for a Clinician Packet, which tasks need handoff, and where escalation is preserved.

Research partners

Source-grounded plans

Run consented observational pilots with explicit missingness, device tier, standards evidence, subgroup calibration, and outcome-window capture.

Employers and payers

Aggregate value

Evaluate CarePlan packet readiness, compliance, burden, avoided duplicate testing, functional days, and privacy-safe cohort summaries.

Individuals

Personal utility first

Keep insight useful while packaging source receipts, medicine context, and clinician questions when care review is needed.

No diagnosis, treatment, insulin dosing, medication adjustment, or disease-prevention guarantee.
Every model family reports source coverage, missing inputs, confidence, next validation step, and prohibited uses.
Medicine and supplement context is database-backed when possible, with manual fallback clearly labeled.
SleepInsight summaries carry source fidelity, hard sanity caps, correction labels, and non-diagnostic breathing-load boundaries before personal or cohort use.
CarePlan status is evidence-backed: InVivo can prepare patient-owned packets and Triager handoff context, while clinician verification, medication, order, photo, high-risk tasks, documentation, export, and plan mutation require the care workflow.
Causal evidence moves through plausibility, retrospective checks, target-trial emulation, n-of-1 pilots, prospective cohorts, pragmatic trials, and external validation.
Outputs can be withheld when data is missing, unsafe, too sparse, or outside the wellness and clinician-discussion boundary.